Effect of ozonation on resistance of ovine and human erythrocytes to hypothermic storage

Long-term hypothermic storage of animal blood can lead to the loss its quality and cause complications in recipient animals after transfusion, so search for new methods increasing preservation erythrocytes continues. The article presents data ozonation effect on rate ovine human during with Alsever’s solution mannitol medium. Hemolysis, osmotic fragility distribution density by sphericity index were determined at different stages storage. control had a lower resistance compared erythrocytes; however, their did not change significantly 8 weeks, erythrocytes, it increased. Storage longer than weeks led sharp hemolysis, while level hemolysis was that erythrocytes. Preservation ozonated is higher non-ozonated ones prolonged red cells depended composition media. Hypothermal up shift according towards spheroidization cells; medium mannitol, number flattened cell forms After most high indices. Pretreatment sheep ozone allows be kept closer long-term storage, which especially pronounced Ovine retained ability form rosettes T-lymphocytes 12 weeks. Thus, pretreatment use as part could an approach improve preserved